First, Apple put the kibosh on the Flash-to-native-app compiler.
Now they’ve killed Scheme/Gambit-C and likely MonoTouch.
PhoneGap and its ilk are safe (for now), but this emblematic of Apple’s approach to third-party app development. It’s the price you pay for playing in someone else’s sandbox.
It’s a tidy sandbox, with rounded, rubberized edges and a bucket from FAO Schwarz. But it’s also sitting on the beach. When the industry grows up, it will end up there, embracing the open standards of the web over the passing benefits of a technocratic, on-deck distribution platform.